Aprile 27, 2021
2021
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Duchenne Muscular Dystrophy: a systematic review and quantification of the economic burden of disease
Autori: G.L. Colombo, G.M. Bruno, S. Di Matteo, C. Martinotti Introduction Duchenne muscular dystrophy (DMD) is a lethal X-linked recessive neuromuscular disorder caused by mutations in the dystrophin gene that result in absent or insufficient functional dystrophin, a cytoskeletal protein essential for the development, stabilization and function of myofibers. Consequently, progressive skeletal, smooth and cardiac [...]